hemostasis controls


AggRAM - Advanced Modular System for Platelet Aggregation Ristocetin Cofactor

Platelet Aggregation Reagents

Helena's platelet reagents provide outstanding stability and performance at affordable pricing. Reagents are optimized for use with AggRAM, but may be used on any turbidometric aggregometer of similar quality.


Ristocetin Cofactor Reagents

Ristocetin Cofactor is more sensitive than RIPA to mild reductions in vWF and more often used to monitor therapy in vWD patients. Kit includes ristocetin, formalinized platelets, S.A.R.P., abnormal control and tris-buffered saline.


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AggRAM Accessories and Supplies

Cat. No. Item
1473 Siliconized Cuvettes for AggRAM, 200/pkg
1479 Scale Set Solutions (650 nm) for Platelet
Assays, 1 each Low and High Calibrator
1489 AggRAM Stir Bars, 30/pkg
9139 Service Manual for AggRAM


Platelet Aggregation Reagents

Cat. No. Item
5366 ADP, 2 x 1 mL
5367 Epinephrine, 2 x 1 mL
5368 Collagen, 2 x 1 mL
5369 Platelet Aggregation Kit (5366, 5367, 5368)
5199 Ristocetin (for RIPA), 10 x 0.5 mL
5365 Tris-Buffered Saline, 1 x 125 mL


Ristocetin Cofactor Reagents

Cat. No. Item
5370 Ristocetin Cofactor Kit, 60 tests
5371 Lyophilized Platelets, 5 x 5 mL
5373 Risto Cofactor Abn Control, 5 x 0.5 mL
5372 Ristocetin (10 mg/mL), 5 x 1.5 mL
5365 Tris-buffered Saline, 1 x 125 mL
5356 Lyophilized Platelets, 5 x 10 mL


PACKS-4 Accessories and Replacement Parts

Cat. No. Item
1463 Air Filters for PACKS-4, 3/pkg
1473 Siliconized Cuvettes for AggRAM and PACKS-4, 200/pkg
1474 PACKS-4 Stir Bars, 30/pkg
1475 Disposable Pipette Tips (1-200 μL), 1000/pkg
1479 Scale Set Solutions (650 nm) for Platelet Assays,
1 each Low and High Calibrator


pt and aptt fibrinogen assays
Cat. No. Item
1484 AggRAM Analyzer
1486 AggRAM Module

Warranty and Service Information

The AggRAM, for platelet aggregation and ristocetin cofactor testing offers unsurpassed precision, ease of use and flexibility. AggRAM couples four-channel laser optic modules with a powerful Windows interface. Up to two modules can be run per Remote Analyzer computer, providing up to eight channels to handle your workload.

Advanced Laser Optics

Unlike the tungsten lamp optics of old, the AggRAM uses a laser diode to provide beautiful precision across all channels. Upon start-up, AggRAM performs a laser balance check to ensure reproducibility day to day, year to year. Advanced optics coupled with an improved algorithm for slope calculation greatly improve precision for ristocetin cofactor testing.


Powerful, User-Friendly Interface
The AggRAM system software takes full advantage of the Windows platform. On-screen prompts step users through testing. The ability to open multiple windows greatly increases efficiency. For instance, watch the channel display in real time in one window while starting a new worklist in another. Open a third window and print previous runs or observe any combination of channels. Additional features include:

• Three levels of password protection, from user to administrator
• Quick access to data input screens
• Barcode and bi-directional LIS capable

Data Handling Features
Automatically calculates slope and max % aggregation; displays and print lag phase; automatically calculates curves and smooths; reference overlay

Customized Reports
Includes data from one channel or four, one patient or the whole run; pulls from data archives to profile patient results over time.

Quality Control
Evaluates and charts QC for ristocetin cofactor based on Westgard rules; generates Levy-Jennings charts, standard curves, etc with an integral action log.


AggRAM Specifications


Test Types: Platelet Aggregation and Ristocetin Cofactor
Absorbance Range: 0.0 to 2.0 O.D.
Measuring Wavelength: 650 nm
Optical Chambers per module: Four chambers for combined or individual measurements
Cuvettes: 8 mm x 60 mm (silicone coated glass)

Stir Bars: 3.5 mm x 4 mm (coated magnet)
Incubation and Reaction Temperature: 37°C +/-1°C
Graphs: -20% to 110% activity (+/- 0.5%) versus time
Instrument Operating Environment: Ambient Temperature Range 15° to 30°C (59° to 86°F)
Input Power: 110/220 Vac, 50/60 Hz, 1200 Watts Maximum
Dimensions: 6" (15.24 cm) Tall x 10" (25.40 cm) Wide x 17" (43.18 cm) Deep
Weight: < 15 lbs (6.75 kg)

Intel Core i7 or equivalent processor
Microsoft - Windows 10 Professional x64
8 GB RAM or higher
500 GB Internal storage drive
LCD Monitor (800 x 600 or higher resolution)
Keyboard and Mouse
Windows 10 Compatible Color Inkjet Printer