Helena Plateletworks Platelet Function Kits
Plateletworks - Platelet Function Kits

The POPULAR trial put Plateletworks® on the short list of platelet function assays that actually work to catch non-responders to the anti-platelet drug Plavix® (clopidogrel) at higher risk for cardiovascular events. Plateletworks can be used anytime there are general concerns about the effect of drug therapies on platelet function. Turnaround is about 5--minutes using traditional agonists including ADP, collagen and arachidonic acid and a standard impedance cell counter. Plateletworks is much more cost-effective than other platelet function assays as well. Contact us for more information or an in-lab demonstration.
Plavix is a registered trademark of Sanofi-Aventis.

Plateletworks by the Numbers

Plateletworks makes sense not only from a technologic viewpoint, but from a cost containment and blood conservation view as well. 2 minutes

Plateletworks provides % inhibition, % Aggregation and CBC using ADP, Collagen or Arachadonic Acid agonists in 2 minutes.

The reimbursement margin for the Plateletworks assay is $15.83. Cost per test for Plateletworks ADP is $14.60 USB and the 2012 average National Reimbursement Limit for CPT Code 85576 is $30.43 USB. That leaves a favorable reimbursement margin of $15.83.  



50 percent  

50% - That's the reduction in platelet usage documented in a retrospective 6 month study of platelet usage using Plateletworks data to guide transfusion decisions. Blood products are precious commodity not to mention the $500 a unit cost for platelets.

POPULAR Platelet Function Assays: Plateletworks Works!

Dr. Nicoline Breet and colleagues at The San Antonius Center for Platelet Function Research in the Netherlands studied 1, 069 patients on clopidogrel undergoing elective PCI with stent implant. They noted that up to 36% of patients do not achieve an optimal degree of platelet inhibition in response to taking clopidogrel. A head-to-head comparison of platelet function assays was undertaken, including laboratory-based light transmittance PRP platelet aggregometry, Helena Plateletworks and five other assays to see if the clinical outcome of these patients could be predicted by their degree of platelet inhibition.  The primary endpoints were the occurrence of an adverse cardiac event, including death, MI, stent thrombosis within one year, as well as incidence of major or minor bleeding.
Of the seven assays studied, only traditional aggregometry, Plateletworks and one other assay were able to identify patients at higher risk for an adverse cardiac event. None were predictive of TIMI major or minor bleeding.  The study results were presented at the American Heart Association Scientific Session in November of 2009 and were reported on the online cardiology site, the heart.orghttp://www.theheart.org/article/1021875.do

Ichor II AnalyzerICHOR II Analyzer

Special Offer: Ichor II Free to Qualified Users

For a limited time, Helena is providing the Ichor® II analyzer for use free of charge to qualified Plateletworks® reagent users in the United States.

The Ichor II is a lower-cost impedance cell counter for Plateletworks platelet function and general hematology testing at the point of care. When used with Plateletworks reagents, the Ichor II system provides a hematology profile with a standard CBC, as well as platelet count and platelet aggregation/inhibition in under five minutes. Testing is simple. Just add whole blood to an EDTA baseline reagent tube and your choice of agonist tubes and run a standard cell count. It’s that simple. Plateletworks can be used to screen for anything affecting platelet function.

For ease of use, Ichor II offers cap piercing capability, reagent inventory management and supports use of a keyboard, barcode scanner and printer. Contact us to discuss your testing needs. Or call 800-231-5663.


Cat. No. Item
5880 ICHOR II Analyzer
5884 ICHOR II Diluent Solution (20L)
5885 ICHOR II Rinse Solution (5L)
5886 ICHOR II Lyse Reagent (500L)
5887 ICHOR II Tri-Level Control
5889 ICHOR II Paper
5881 ICHOR II 5.5L Diluent - Plastic Container
5882 ICHOR II E-Z Cleaner (100L)
5883 ICHOR II Probe Cleanser (1 x 17 mL)

ICHOR II Specifications:

Tests: Hemoglobin, Hematocrit, RBC Count, RBC Indices (MCV, MCH, MCHC), WBC Count, Platelet Count, MVP, Whole Blood Platelet Aggregation with ADP, Collagen, Arachidonic Acid
Reagent Delivery System: External reagent and waste container bottles with reagent inventories managed by the instrument.
Linearity: RBC (x1012 cells/µL): 0.2 to 8.0 ±0.05 (or ±5%)
                  WBC (x109 cells/µL): 0.3 to 99.9 ±0.3 (or ±5%)
                  Hemoglobin (g/dL): 10 to 250 ±2 (or ±3%)
                  Platelets (x109 cells/µL): 10 to 999 ±10 (or ±10%)
Sample: Closed-tube sampling requires only 13 µL of whole blood
Throughput: 60 seconds per sample; 60 samples per hour
Operating Mode: Sequential, single channel analysis
Operating Principle: Electronic impedance measurement
Quality Control Features: Integrated QC program provides LJ, mean, SD, CV% analysis with graphing
User Interface: 23-key alphanumeric keypad (PS/2 keyboard optional)
Display: 800 x 600 character color LCD
Printer: Optional
Memory: Stores maximum of 35,000 sample results
Power Requirements: 100 to 240 Vac, 50/60 Hz
Operating Environment: 15ºC to 30ºC (59 to 86ºF)
Dimensions: 15.4"W x 16.3"D x 18"D (39.1W x 41.5D x 45.7H cm)
Weight: 55 lbs. (25 kgs)


25 ADP Agonist Reagent Tubes and 25 EDTA Baseline TubesPlateletworks ADP Kit

Cat. No. Item
5860 Plateletworks ADP Kit

Kit includes 25 ADP Agonist Reagent Tubes and 25 EDTA Baseline Tubes



25 Collagen Agonist Reagent Tubes and 25 EDTA Baseline TubesPlateletworks Collagen Kit

Cat. No. Item
5862 Plateletworks Collagen Kit

Kit includes 25 Collagen Agonist Reagent Tubes and 25 EDTA Baseline Tubes



25 AA Agonist Reagent Tubes and 25 EDTA Baseline TubesPlateletworks Arachidonic Acid Kit

Cat. No. Item
5864 Plateletworks Arachidonic Acid Kit

Kit includes 25 AA Agonist Reagent Tubes and 25 EDTA Baseline Tubes



10 ADP, 10 Collagen and 10 AA Agonist Tubes with 10 EDTA Baseline TubesPlateletworks Combo-10 Kit

Cat. No. Item
5854 Plateletworks Combo-10 Kit

Kit includes 10 ADP, 10 Collagen and 10 AA Agonist Tubes with 10 EDTA Baseline Tubes


15 ADP and 15 Collagen Agonist Reagent Tubes and 15 EDTA Baseline TubesPlateletworks Combo-15 Kit

Cat. No. Item
5850 Plateletworks Combo-15 Kit

Kit includes 15 ADP and 15 Collagen Agonist Reagent Tubes and 15 EDTA Baseline Tubes


Plateletworks Combo-25 Kit

Cat. No. Item
5852 Plateletworks Combo-25 Kit

Kit includes 25 ADP and 25 Collagen Agonist Reagent Tubes







Helena Plateletworks

In about two minutes, monitor Platelet Count and real Platelet Aggregation or Inhibition at the point of care using traditional ADP, collagen or Arachidonic acid agonists. All that's needed is an impedance cell counter and Plateletworks.

• Platelet Aggregation

Platelet Inhibition

Platelet Count


By directly monitoring the platelet's ability to form an aggregate, it's a direct measurement of the platelet's ability to contribute to a thrombus. Plateletworks can be used to monitor all mechanisms which affect platelet aggregation:

• Physiological conditions such as fibrinolytic damage to glycoprotein la

• Aspirin and ADP inhibitors (clopidogrel, ticlopene)

• Glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, tirofiban)

• Plus Arachidonic Acid agonist is the only aspirin screening assay suitable for patients on both clopidogrel and aspirin



Plateletworks Brochure

Plateletworks Brochure